Search results for "Digital microscope"
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Characterization of a compact low-cost Stokes lens for astigmatism compensation in optical instruments
2020
Variable power cross-cylinder lenses (or Stokes lenses) have been widely known in the literature for decades. In this paper, we describe how to build a low-cost Stokes lens and discuss its calibration and its application to two significant cases. The construction is in virtue of a phoropter’s Risley prism mount for assembling a couple of equal but opposite sign cylindrical lenses (we have selected ± 1.50 D). Thus, variable astigmatic power is achieved by relative rotation of the lenses in opposite directions, and the resulting astigmatic axis is defined by the global rotation of the device. Calibration measurements are performed using an automatic lensmeter (Topcon CL-300) and an aberromete…
Probabilistic classification of intracranial gliomas in digital microscope images based on EGFR quantity
2009
A glioma is a type of cancer occurring, in the majority of cases, in the brain. The World Health Organization (WHO) assigns a grade from I to IV to this tumor, with I being the least aggressive and IV being the most aggressive. In glioma cells of grade IV the Epidermal Growth Factor Receptors (EGFRs) are over expressed. In this paper we hypothesize that this overexpression occurs also for gliomas of grades I to III. Moreover, we present a medical study aiming to determine the correlation between the WHO classification and the EGFR quantity in glioma tissue. We define five quantity classes for EGFR. First, results of immunohistochemical staining on brain glioma slices, which visualize the EG…